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Allergy medications: Know your options

Decongestants

Decongestants are used for quick, temporary relief of nasal and sinus congestion. They can cause trouble sleeping, headache, increased blood pressure and irritability. They're not recommended for people with high blood pressure, cardiovascular disease, glaucoma or hyperthyroidism.

Pills and liquids

Oral decongestants relieve nasal and sinus congestion caused by hay fever (allergic rhinitis). Many decongestants, such as pseudoephedrine (Sudafed), are available over-the-counter.

A number of oral allergy medications contain a decongestant and an antihistamine. Examples include:

  • Cetirizine and pseudoephedrine (Zyrtec-D 12 Hour)
  • Desloratadine and pseudoephedrine (Clarinex-D)
  • Fexofenadine and pseudoephedrine (Allegra-D)
  • Loratadine and pseudoephedrine (Claritin-D)

Nasal sprays and drops

Nasal decongestant sprays and drops relieve nasal and sinus congestion if used only for a short time. Repeated use of these drugs for more than three consecutive days may result in a cycle where congestion recurs or gets worse. Examples include:

  • Oxymetazoline (Afrin)
  • Tetrahydrozoline (Tyzine)

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