Entire house

1. Temperature and humidity. Hot, humid houses are breeding grounds for dust mites and mold. Maintain the temperature between 68 F (20 C) and 72 F (22 C) and keep relative humidity no higher than 50 percent. Clean or replace small-particle filters in central heating and cooling systems and in room air conditioners at least once a month.
2. Pests. Control cockroaches and mice with inexpensive traps from the hardware store. If that's not effective, hire a professional exterminator. To remove allergy-triggering insect and mouse residue, thoroughly vacuum carpeting and wash hard surfaces. To prevent re-infestation, seal cracks or other possible entryways.
3. Mold. Close doors and windows during warm weather and use air conditioning and dehumidifiers. Remove nonwashable contaminated materials such as carpeting. Clean washable material with a solution of 5 percent chlorine bleach, and wear a protective mask when cleaning away mold. Check the roof and ceilings for water leaks.
4. Weekly cleaning routine. Damp-mop wood or linoleum flooring and vacuum carpeting. Use a vacuum cleaner with a small-particle or a high-efficiency particulate air (HEPA) filter. Use a damp cloth to clean other surfaces, including the tops of doors, windowsills and window frames. If you have allergies, either wear a dust mask or get someone who doesn't have allergies to do this job.
5. Smoking. Don't allow smoking anywhere inside your house.