How atypical antidepressants work

Atypical antidepressants ease depression by affecting chemical messengers (neurotransmitters) used to communicate between brain cells. Like most antidepressants, atypical antidepressants work by ultimately effecting changes in brain chemistry and communication in brain nerve cell circuitry known to regulate mood, to help relieve depression.

Atypical antidepressants change the levels of one or more neurotransmitters, such as dopamine, serotonin or norepinephrine.