Mayo Clinic Care Network Content
Articles

Atypical antidepressants

Possible side effects of atypical antidepressants

Side effects may occur with antidepressants, including atypical antidepressants, though some people may not experience any. Some side effects may go away after a time, while others may lead you and your doctor to try a different medication.

Because of the different ways atypical antidepressants work, each has unique characteristics and varying possible side effects. For example:

  • Most of the atypical antidepressants list dry mouth, dizziness or lightheadedness as possible side effects.
  • Some antidepressants may help you sleep and are best taken at night, while others may cause insomnia.
  • Some antidepressants may cause constipation, while others may increase the risk of diarrhea.
  • Some antidepressants may increase your appetite, resulting in weight gain, while others may cause nausea.
  • Some antidepressants are more likely than others to cause sexual side effects.

Which antidepressant is best for you depends on a number of issues, such as your symptoms and any other health conditions you may have. Ask your doctor and pharmacist about the most common possible side effects for your specific antidepressant and read the patient medication guide that comes with the prescription.