Flu-like symptoms

Headache and muscle aches — typically accompanied by fatigue — are common side effects of hepatitis C medications. You can cope with these signs and symptoms by:

• Taking an over-the-counter medication such as acetaminophen (Tylenol, others) or ibuprofen (Advil, Motrin IB, others) before each injection and as needed while the symptoms last — if your doctor says it's safe for you
• Giving yourself peginterferon alfa injections, which a member of your care team can usually show you how to do, shortly before bedtime
• Drinking plenty of fluids
• Getting enough rest
• Avoiding strong sunlight and bright indoor lights to prevent headache
• Using warm, moist heat on achy muscles