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COVID-19 vaccines: Get the facts

Coronavirus vaccine research Coronavirus vaccine challenges Pathways to develop and produce a COVID-19 vaccine The vaccine development timeline How to protect yourself and prevent COVID-19 infection Content What are the benefits of getting a COVID-19 vaccine? Should I get the COVID-19 vaccine even if I've already had COVID-19? What COVID-19 vaccines have been authorized or approved and how do they work? Can a COVID-19 vaccine give you COVID-19? What are the possible general side effects of a COVID-19 vaccine? What are the long-term side effects of the COVID-19 vaccines? Can COVID-19 vaccines affect the heart? What is the connection between the Janssen/Johnson & Johnson COVID-19 vaccine and Guillain-Barre syndrome? What are the symptoms of a blood clotting reaction to the Janssen/Johnson & Johnson COVID-19 vaccine? Do the COVID-19 vaccines protect against the COVID-19 variants? Are COVID-19 vaccines free? Can I get a COVID-19 vaccine if I have an existing health condition? Is it OK to take an over-the-counter pain medication before or after getting a COVID-19 vaccine? Is there anyone who should not get a COVID-19 vaccine? What are the signs of an allergic reaction to a COVID-19 vaccine? Can I get a COVID-19 vaccine if I have a history of allergic reactions? Can pregnant or breastfeeding women get the COVID-19 vaccine? Can a COVID-19 vaccine affect fertility or menstruation? What COVID-19 vaccine has been approved for kids? If children don’t frequently experience severe illness with COVID-19, why do they need a COVID-19 vaccine? How did the FDA determine the safety and effectiveness of the Pfizer-BioNTech COVID-19 vaccine for use in kids ages 12 through 15? Can I stop taking safety precautions after getting a COVID-19 vaccine? Can I still get COVID-19 after I’m vaccinated? Are COVID-19 vaccine additional doses or boosters recommended?

Do the COVID-19 vaccines protect against the COVID-19 variants?

In the U.S., the delta (B.1.617.2) variant is now the most common COVID-19 variant. It is nearly twice as contagious as earlier variants and might cause more severe illness.

While research suggests that COVID-19 vaccines are slightly less effective against the variants, the vaccines still appear to provide protection against severe COVID-19. For example:

  • Early research from the U.K. suggests that, after full vaccination, the Pfizer-BioNTech COVID-19 vaccine is 88% effective at preventing symptomatic COVID-19. The vaccine is also 96% effective at preventing severe disease with COVID-19 caused by the delta variant.
  • Early research from Canada suggests that, after one dose, the Moderna COVID-19 vaccine is 72% effective at preventing symptomatic COVID-19 caused by the delta variant. One dose of the vaccine is also 96% effective at preventing severe disease with COVID-19 caused by the delta variant.
  • The Janssen/Johnson & Johnson COVID-19 vaccine is 85% effective at preventing severe disease with COVID-19 caused by the delta variant, according to data released by Johnson & Johnson.