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COVID-19 vaccines: Get the facts

Coronavirus vaccine research Coronavirus vaccine challenges Pathways to develop and produce a COVID-19 vaccine The vaccine development timeline How to protect yourself and prevent COVID-19 infection Content What are the benefits of getting a COVID-19 vaccine? Should I get the COVID-19 vaccine even if I've already had COVID-19? What COVID-19 vaccines have been authorized or approved and how do they work? Can a COVID-19 vaccine give you COVID-19? What are the possible general side effects of a COVID-19 vaccine? What are the long-term side effects of the COVID-19 vaccines? Can COVID-19 vaccines affect the heart? What is the connection between the Janssen/Johnson & Johnson COVID-19 vaccine and Guillain-Barre syndrome? What are the symptoms of a blood clotting reaction to the Janssen/Johnson & Johnson COVID-19 vaccine? Do the COVID-19 vaccines protect against the COVID-19 variants? Are COVID-19 vaccines free? Can I get a COVID-19 vaccine if I have an existing health condition? Is it OK to take an over-the-counter pain medication before or after getting a COVID-19 vaccine? Is there anyone who should not get a COVID-19 vaccine? What are the signs of an allergic reaction to a COVID-19 vaccine? Can I get a COVID-19 vaccine if I have a history of allergic reactions? Can pregnant or breastfeeding women get the COVID-19 vaccine? Can a COVID-19 vaccine affect fertility or menstruation? What COVID-19 vaccine has been approved for kids? If children don’t frequently experience severe illness with COVID-19, why do they need a COVID-19 vaccine? How did the FDA determine the safety and effectiveness of the Pfizer-BioNTech COVID-19 vaccine for use in kids ages 12 through 15? Can I stop taking safety precautions after getting a COVID-19 vaccine? Can I still get COVID-19 after I’m vaccinated? Are COVID-19 vaccine additional doses or boosters recommended?

Coronavirus vaccine challenges

Past research on vaccines for coronaviruses has also identified some challenges to developing a COVID-19 vaccine, including:

  • Ensuring vaccine safety. Several vaccines for SARS have been tested in animals. Most of the vaccines improved the animals' survival but didn't prevent infection. Some vaccines also caused complications, such as lung damage. A COVID-19 vaccine will need to be thoroughly tested to make sure it's safe for humans.
  • Providing long-term protection. After infection with coronaviruses, re-infection with the same virus — though usually mild and only happening in a fraction of people — is possible after a period of months or years. An effective COVID-19 vaccine will need to provide people with long-term infection protection.
  • Protecting older people. People older than age 50 are at higher risk of severe COVID-19. But older people usually don't respond to vaccines as well as younger people. An ideal COVID-19 vaccine would work well for this age group.

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