Interactions

Possible interactions include:

• Anticoagulants and anti-platelet drugs, herbs and supplements. These types of drugs, herbs and supplements reduce blood clotting. Taking L-arginine with them might increase the risk of bleeding.
• Blood pressure drugs, herbs and supplements. L-arginine might lower blood pressure in people who have high blood pressure. Combining use of L-arginine with a blood pressure drug, herb or supplement might increase the risk of blood pressure becoming too low.
• Diabetes drugs, herbs and supplements. L-arginine might decrease blood sugar levels in people with diabetes. If you're taking diabetes drugs, herbs or supplements, your dosage might need to be adjusted.
• Isoproterenol (Isuprel). Use of this heart medication with L-arginine might cause your blood pressure to become too low.
• Nitrates. Use of this chest pain medication with L-arginine might cause your blood pressure to become too low.
• Water pills (potassium-sparing diuretics). Don't take L-arginine with amiloride (Midamor), spironolactone (Aldactone, Carospir) or triamterene (Dyrenium). These medications can increase potassium levels, increasing the risk of developing a higher than normal level of potassium in your blood (hyperkalemia).
• Sildenafil (Revatio, Viagra). Use of this erectile dysfunction medication with L-arginine might cause your blood pressure to become too low.