Safety and side effects

Melatonin taken orally in appropriate amounts is generally safe. Melatonin can cause:

• Headache
• Dizziness
• Nausea
• Drowsiness

Less common melatonin side effects might include short-lasting feelings of depression, mild tremor, mild anxiety, abdominal cramps, irritability, reduced alertness, confusion or disorientation.

Because melatonin can cause daytime drowsiness, don't drive or use machinery within five hours of taking the supplement.

Don't use melatonin if you have an autoimmune disease.