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Osteoporosis treatment: Medications can help

Should I take a drug holiday from bisphosphonates?

The risk of developing atypical femoral fracture or osteonecrosis of the jaw tends to increase the longer you take bisphosphonates. So your doctor might suggest that you temporarily stop taking this type of drug. This practice is known as a drug holiday.

However, even if you stop taking the medication, its positive effects can persist. That's because after taking a bisphosphonate for several years, the medicine remains in your bone.

Because of this lingering effect, most experts believe that it's reasonable for people who are doing well during treatment — those who have not broken any bones and are maintaining bone density — to consider taking a holiday from their bisphosphonate after taking it for five years.