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St. John's wort

Overview Evidence Our take Safety and side effects Interactions

Safety and side effects

When taken orally for up to 12 weeks in appropriate doses, St. John's wort is generally considered safe. However, it may cause:

  • Agitation and anxiety
  • Dizziness
  • Diarrhea, constipation and stomach discomfort
  • Dry mouth

Other side effects may include:

  • Fatigue and insomnia
  • Headache
  • Increased sensitivity to sunlight (photosensitivity)

There isn't enough information about the safety of using St. John's wort topically.

Don't use St. John's wort during pregnancy or while breastfeeding.