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Vitamin B-6

Overview Evidence Our take Safety and side effects Drug interactions

Safety and side effects

Consuming vitamin B-6 through food appears to be safe, even in excessive amounts.

When used as a supplement in appropriate doses, vitamin B-6 is likely safe.

However, taking too much vitamin B-6 from supplements can cause:

  • A lack of muscle control or coordination of voluntary movements (ataxia)
  • Painful, disfiguring skin lesions
  • Heartburn and nausea
  • Sensitivity to sunlight (photosensitivity)
  • Numbness
  • Reduced ability to sense pain or extreme temperatures