Mayo Clinic Care Network Content
Definitions

SSRI discontinuation syndrome


Overview

SSRI discontinuation syndrome refers to symptoms that may occur when a person stops taking SSRI antidepressants.

Symptoms

Symptoms can be flu-like and include nausea, sleeplessness, anxiety, and irritability.

Treatments

It may be avoided by a slow reduction of the amount of antidepressant or by a switch to another SSRI drug.