Overview

Corticobasal degeneration is a rare disease in which areas of your brain shrink and your nerve cells degenerate and die over time. The disease affects the area of the brain that processes information and brain structures that control movement. This degeneration results in growing difficulty in movement on one or both sides of your body.

The condition may cause you to have poor coordination, stiffness, difficulty thinking, trouble with speech or language, or other problems.