Symptoms

Signs and symptoms of corticobasal degeneration include:

• Difficulty moving on one or both sides of the body, which gets worse over time
• Poor coordination
• Trouble with balance
• Stiffness
• Abnormal postures of the hands or feet, such as a hand forming a clenched fist
• Muscle jerks
• Difficulty swallowing
• Abnormal eye movements
• Trouble with thinking, speech and language

Corticobasal degeneration progresses over six to eight years. Eventually, people with corticobasal syndrome can become unable to walk.