Diseases and Conditions
Cryoglobulinemia
Overview
Symptoms
Causes
Risk factors
Diagnosis
Treatment
Lifestyle and home remedies
Preparing for an appointment
Symptoms
Symptoms usually come and go, and may include:
- Skin lesions. Most people with cryoglobulinemia develop purplish skin lesions on their legs. In some people, leg ulcers also occur.
- Joint pain. Symptoms resembling rheumatoid arthritis are common in cryoglobulinemia.
- Peripheral neuropathy. Cryoglobulinemia can damage the nerves at the tips of your fingers and toes, causing numbness and other problems.