Diseases and Conditions
Granulomatosis with polyangiitis
Overview
Symptoms
Causes
Risk factors
Complications
Diagnosis
Treatment
Coping and support
Preparing for an appointment
Causes
The cause of granulomatosis with polyangiitis isn't known. It's not contagious, and there's no evidence that it's inherited.
The condition can lead to inflamed, narrowed blood vessels and harmful inflammatory tissue masses (granulomas). Granulomas can destroy normal tissue, and narrowed blood vessels reduce the amount of blood and oxygen that reaches your body's tissues and organs.
