Overview

Malignant peripheral nerve sheath tumors are a rare type of cancer that occurs in the lining of the nerves that extend from the spinal cord into the body. Malignant peripheral nerve sheath tumors used to be called neurofibrosarcomas.

Malignant peripheral nerve sheath tumors can occur anywhere in the body, but most often occur in the deep tissue of the arms, legs and trunk. They tend to cause pain and weakness in the affected area and may also cause a growing lump or mass.

Malignant peripheral nerve sheath tumors are typically treated with surgery. In certain cases, radiation therapy and chemotherapy also may be recommended.