Diagnosis

You may have one or more of the following tests to diagnose solitary rectal ulcer syndrome:

• Sigmoidoscopy. During this test, your doctor inserts a thin, flexible tube with a tiny camera into your rectum to examine your rectum and part of your colon. If a lesion is found, your doctor may take a tissue sample for laboratory testing.
• Ultrasound. This imaging technique uses sound waves to create pictures. Your doctor may recommend an ultrasound to help differentiate solitary rectal ulcer syndrome from other conditions.

• Other imaging studies. Your doctor may order an imaging study called defecation proctography. In this study, a soft paste made of barium is inserted into your rectum. You then pass the barium paste as you would stool. The barium shows up on X-rays and may reveal a prolapse or problems with muscle function and muscle coordination.

  Specialized centers may offer a similar test called magnetic resonance defecography. This test is done with a magnetic resonance imaging machine and provides a 3D image of the rectum.