Complications

Complications of systemic mastocytosis can include:

• Anaphylactic reaction. This severe allergic reaction includes signs and symptoms such as rapid heartbeat, fainting, loss of consciousness and shock. If you have a severe allergic reaction, you may need an injection of epinephrine.
• Blood disorders. These can include anemia and poor blood clotting.
• Peptic ulcer disease. Chronic stomach irritation can lead to ulcers and bleeding in your digestive tract.
• Reduced bone density. Because systemic mastocytosis can affect your bones and bone marrow, you may be at risk of bone problems, such as osteoporosis.
• Organ failure. A buildup of mast cells in body organs can cause inflammation and damage to the organ.