Bed-wetting that starts in adulthood (secondary enuresis) is uncommon and requires medical evaluation.

Causes of adult bed-wetting may include:

• A blockage (obstruction) in part of the urinary tract, such as from a bladder stone or kidney stone
• Bladder problems, such as small capacity or overactive nerves
• Diabetes
• Enlarged prostate
• Medication side effect
• Neurological disorders
• Obstructive sleep apnea
• Urinary tract infection

Tests and procedures used to determine the cause of adult bed-wetting include:

• Physical exam
• Urine tests
• Urologic tests
• Neurological evaluation

Treatment of adult bed-wetting is directed at the underlying cause, when possible.