Tests and Procedures

Rheumatoid factor

Results

A positive rheumatoid factor test result indicates that a high level of rheumatoid factor was detected in your blood. A higher level of rheumatoid factor in your blood is closely associated with autoimmune disease, particularly rheumatoid arthritis. But a number of other diseases and conditions can raise rheumatoid factor levels, including:

  • Cancer
  • Chronic infections
  • Inflammatory lung diseases, such as sarcoidosis
  • Mixed connective tissue disease
  • Sjogren's syndrome
  • Systemic lupus erythematosus

Some healthy people — particularly older individuals — have positive rheumatoid factor tests, though it's not clear why. And some people who have rheumatoid arthritis will have low levels of rheumatoid factor in their blood.

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