Onabotulinumtoxin type A (Botox)

How it works

Injections of Botox into the bladder muscle might benefit people who have an overactive bladder. Botox blocks the actions of acetylcholine and paralyzes the bladder muscle.

Botox might be helpful for people who haven't responded to other medications. Benefits can last several months. Your doctor might recommend repeat injections once or twice a year.

Side effects

Studies have found that Botox significantly improves symptoms of incontinence and causes few side effects. Some research indicates it may increase urinary tract infections, but the data aren't conclusive.

The Food and Drug Administration (FDA) warns that adverse reactions including respiratory arrest and death may occur after the use of Botox for both approved and unapproved uses.